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G. Asher Newsome

Physical Scientist

Background And Education

Education And Training

Professional Biography

  • I approach mass spectrometry analysis from a fundamental perspective which informs my application work. Most of my work at the Museum Conservation Institute studies small molecules using high resolution MS, ambient ionization, and/or GCMS.

    I have a major interest is in modifying ambient sampling and ionization techniques for cultural heritage and conservation science applications. Much of my current research involves developing instrumental methods for analyzing intact objects which are both too sensitive for microsampling and too dimensionally large to be positioned immediately adjacent to a mass spectrometer for conventional ambient sampling techniques. This technical challenge of analyzing sensitive, intact objects also involves close work with curators, conservators, and other interested parties to determine an acceptable level of “invasiveness” for the sampling.

Awards And Honors

Research And Grants

Keywords

  • ambient ionization
  • mass spectrometry
  • minimally-invasive sampling
  • natural and synthetic materials
  • novel instrumentation

Publications

Selected Publications

Presentations

  • Presentation

    • Newsome, G. Asher. 2020. Ambient Mass Spectrometry of Museum Objects and Materials [presentation]. Seminar to Smithsonian volunteers, September 2, 2020. Washington, DC: Smithsonian Institution.
    • Newsome, G. Asher. 2021. Ambient Sampling and Ionization for Mass Spectrometry of Museum Objects and Materials [presentation]. British Mass Spectrometry Society Ambient Ionisation SIG virtual seminar series, February 4, 2021. British Mass Spectrometry Society.
    • Newsome, G. Asher. 2021. Ambient Sampling and Ionization for Mass Spectrometry of Museum Objects and Materials [presentation]. June 16, 2021. Bordeaux summer school.
    • Newsome, G. Asher. 2020. Ambient Sampling and Ionization for Mass Spectrometry of Museum Objects and Materials [presentation]. Seminar to the Kaveh Jorabchi lab, April 8, 2020. Georgetown University.
    • Newsome, G. Asher. 2020. Ambient Sampling and Ionization for Mass Spectrometry of Museum Objects and Materials [presentation]. Seminar to the NASA Goddard Center, March 4, 2020. Greenbelt, Maryland: NASA.
    • Newsome, G. Asher. 2020. Ambient Sampling and Ionization for Mass Spectrometry of Museum Objects and Materials [presentation]. Seminar to the FDA Center for Food Safety and Applied Nutrition, February 26, 2020. College Park, Maryland: Food and Drug Administration.
    • Newsome, G. Asher. 2018. Ambient Sampling and Ionization of Materials for Mass Spectrometry [presentation]. 2nd Materials Working Group, November 1, 2018. New York, NY.
    • Baglia, Regina A., Ballard, Mary W., and Newsome, G. Asher. 2018. Ambient analysis of historic textiles by DART-MS [presentation]. American Institute for Conservation 46th Annual Meeting, May 1, 2018. Houston, Texas: American Institute for Conservation.
    • Newsome, G. Asher, Alvarez-Martin, Alba, and Kavich, Gwenaelle. 2019. An Interface for Reproducible, Multi-shot Direct Analysis of Solid-phase Microextraction Samples [presentation]. 67th Meeting of the American Society for Mass Spectrometry, June 1, 2019. Atlanta, Georgia: American Society for Mass Spectrometry.
    • Newsome, G. Asher. 2023. Analytical Chemistry and Mass Spectrometry at the Smithsonian Museum Conservation Institute [presentation]. September 1, 2023. Washington, DC: George Washington University.
    • Newsome, G. Asher. 2024. Application and Accessibility Improvements for Real-time, Minimally-invasive, Non-proximate Sampling of Conserved Art Objects [presentation]. International Mass Spectrometry Conference 2024, August 23, 2024. Melbourne, Australia: International Mass Spectrometry.
    • Newsome, G. Asher. 2018. Direct Analysis in Real Time (DART) Mass Spectrometry of Ancient, Historic, and Modern Objects [presentation]. Gordon Research Conference on Scientific Methods in Cultural Heritage, July 1, 2018. Castelldefels, Spain.
    • Newsome, G. Asher. 2017. Direct Analysis in Real Time of Heat-Sensitive Objects without Damage [presentation]. 38th East Coast Ion Chemistry Conference, October 1, 2017. Newark, Delaware.
    • Newsome, G. Asher. 2019. Direct analysis in real time (DART) of Objects [presentation]. 67th Meeting of the American Society for Mass Spectrometry, June 1, 2019. Atlanta, Georgia: American Society for Mass Spectrometry.
    • Alvarez-Martin, Alba, Janssens, K., Kavich, Gwenaelle, and Newsome, G. Asher. 2018. Evaluation of the Discoloration Mechanism of Eosin in Oil Paint by Direct Analysis in Real Time-Mass Spectrometry [presentation]. 66th ASMS Conference on Mass Spectrometry, June 1, 2018. San Diego, California: American Society for Mass Spectrometry.
    • Chen, X., Buchanan, M. G., Glasper, J., Newsome, G. Asher, and Larriba-Andaluz, C. 2021. Flow Optimization of an Ambient Desorption Source for Solvent-free Analysis of Non-proximate Objects [presentation]. 69th Conference of the American Society for Mass Spectrometry, November 1, 2021. Philadelphia, Pennsylvania: American Society for Mass Spectroscopy.
    • Newsome, G. Asher. 2023. From the FDA to the Smithsonian: Creating instrumental solutions for fundamental and applied mass spectrometry [presentation]. US HUPO Webinar, September 1, 2023. US Human Proteome Organization.
    • Birdsall, Erin R., Newsome, G. Asher, Heald, Susan, and Kavich, Gwenaelle. 2024. Investigating volatile contaminant mitigation and object cleaning methods via in-situ¬ SPME sampling [presentation]. 72nd ASMS Conference on Mass Spectrometry and Allied Topics, Anaheim, California: American Society for Mass Spectrometry.
    • Newsome, G. Asher. 2019. Mass Spectrometry of Museum Objects and Materials [presentation]. group meeting at Children’s Hospital of Philadelphia, September 1, 2019. Philadelphia, Pennsylvania.
    • Newsome, G. Asher, Romano, Christine, Lam, Thomas, and Tsang, Jia-sun. 2018. Microsampling, DART-MS, and GC-MS of Metal Soap Protrusions on Aged Oil Paintings [presentation]. 66th ASMS Conference on Mass Spectrometry, June 1, 2018. San Diego, California: American Society for Mass Spectrometry.
    • Newsome, G. Asher and Cleland, Timothy P. 2018. Multimodal Mass Spectrometric Analysis of an 18th-19th Century Cultural Heritage Object [presentation]. 39th East Coast Ion Chemistry Conference, October 1, 2018. Newark, Delaware.
    • Alvarez-Martin, Alba, Newsome, G. Asher, and Kavich, Gwenaelle. 2018. New strategy to detect ‘small’ VOCs in museum collections: Solid Phase Micro-extraction coupled to Direct Analysis in Real Time-Mass Spectrometry (SPME-DART-MS) [presentation]. Gordon Research Conference on Scientific Methods in Cultural Heritage, July 1, 2018. Castelldefels, Spain.
    • Newsome, G. Asher, Martin, Kathleen, and Campbell-Such, Julia. 2020. Non-proximate Ambient Sampling for Solvent-free Analysis of Intact Objects [presentation]. 68th ASMS Conference on Mass Spectrometry and Allied Topics. Virtual conference, June 1, 2020. American Society for Mass Spectrometry.
    • Newsome, G. Asher, Martin, Kathleen, and Campbell-Such, Julia. 2020. Non-proximate Ambient Sampling for Solvent-free Analysis of Intact Objects [presentation]. Chicago Mass Spec Day. Virtual conference, August 14, 2020.
    • Newsome, G. Asher. 2024. Non-proximate sampling of intact Native American baskets with in-line dopant permeation and photoionization [presentation]. March 18, 2024. Columbia, Maryland: Washington Baltimore Mass Spectrometry Discussion Group.
    • Newsome, G. Asher. 2023. Non-proximate sampling of intact Native American baskets with in-line dopant permeation atmospheric pressure photoionization [presentation]. International Mass Spectrometry Conference 2022, August 1, 2023. Maastricht, Netherlands: International Mass Spectrometry.
    • Newsome, G. Asher, Diaz-Granados, Katja S., Caldwell, Joshua D., and Birdsall, Erin R. 2024. Pyrolysis and Thermal Extraction of Polymeric Materials with Suction-driven, Real-time Chemical Ionization Sources and Rapid Polarity Switching [presentation]. 72nd ASMS Conference on Mass Spectrometry and Allied Topics, June 4, 2024. Anaheim, California: American Society for Mass Spectrometry.
    • Newsome, G. Asher. 2022. Sampling, Ambient Mass Spectrometry, and the Philosophy of Damage [presentation]. Scientific Methods in Cultural Heritage Research, July 1, 2022. Les Diablerets, Switzerland.
    • Newsome, G. Asher. 2024. Sampling, Ambient Mass Spectrometry, and the Philosophy of Damage for Cultural Heritage Analysis [presentation]. September 12, 2024. Los Alamos, New Mexico: Los Alamos National Labs.
    • Newsome, G. Asher. 2024. Sampling, Ambient Mass Spectrometry, and the Philosophy of Damage in a Museum Setting [presentation]. February 2, 2024. Kingston, Ottawa, Canada: Queen's Universtiy.
    • Newsome, G. Asher. 2023. Sampling, Ambient Mass Spectrometry, and the Philosophy of Damage in a Museum Setting [presentation]. February 1, 2023. Athens, Georgia: University of Georgia.
    • Newsome, G. Asher. 2022. Surface Sampling, Ambient Mass Spectrometry, and Damage [presentation]. Organic Residue Analysis working group, January 28, 2022.
  • Lawther, Hannah A., Newsome, G. Asher, and Haight-Smith, Vanessa. 2022. Minimally-Invasive Liquid Microjunction Sampling to Identify Dye on a 17th Century Spanish Illuminated Manuscript [presentation]. 70th conference the American Society for Mass Spectrometry, June 1, 2022. Minneapolis, Minnesota: American Society for Mass Spectrometry.

Activities

Professional Service Activities

Affiliation

Contact

Location

Mailing Address

  • 4210 Silver Hill Rd., Suitland, MD 20746